I change the "Mode" in my RIP and my colors are different.

Just changing your 'Mode"  makes your profile invalid.

You must use the 'Mode' that the profile was designed for to make ink limits and color correction valid and controllable.
Quality 5 uses a larger drop size set than Quality 4, even though both are 720 x 720 8 pass, which would place more ink on the media.

Changing the 'Mode' often time completely invalidates a profile.
Changing any of the parameters with alter the 'profile' usually with inconsistant and uncontrollable results.
The diffusion, ink restrictions, ink limits and icc color correction are ALL part of a profile that controls how much ink is placed on the media and what colors those amounts and proportions of inks produce.

Profiling outdoor media is still a bit of an artform.
And color management is critical to being able to control your output.
That means that the color space that the artwork is created in must be defined and controlled so that the RIP can properly interpret that color space and best match it to the profile.

One of the easiest ways to do this is to save the file as a .tif with an embedded profile.